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Donor exchange programs in kidney transplantation: rationale and operational details from the north central donor exchange cooperative

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Title: Donor exchange programs in kidney transplantation: rationale and operational details from the north central donor exchange cooperative
Author(s): Akkina, Sanjeev K.; Muster, Heather; Steffens, Eugenia; Kim, Joseph; Kasiske, Betram L.; Israni, Ajay K.
Subject(s): kidney transplants donor exchange programs
Abstract: The increasing need for kidney transplants has led to innovations such as donor exchange programs. These programs offer transplant recipients with incompatible donors an opportunity to receive a compatible kidney. They also provide an alternative to costly desensitization protocols that have unproven long-term outcomes. Donor exchange programs have multiple options including simple two-pair exchanges to the more complicated domino exchanges or chain donations. The United States is currently limited by regional programs that provide for kidney donor exchanges. However, with the increasing public interest and need for kidney transplants, general nephrologists will be approached with questions about these donor exchange programs. The goal of this review is to discuss donor exchange programs including their role in expanding the donor pool, the various types of exchanges, regional centers that provide these programs, and the process involved in patient enrollment. A general knowledge of donor exchange programs will help providers in discussing options with patients approaching end-stage kidney disease and transplantation.
Issue Date: 2011-01
Publisher: Elsevier
Citation Info: Akkina, S. K., Muster, H., Steffens, E., Kim, S. J., Kasiske, B. L., & Israni, A. K. 2011. Donor exchange programs in kidney transplantation: rationale and operational details from the north central donor exchange cooperative. American Journal of Kidney Diseases, 57(1): 152-158. DOI: 10.1053/j.ajkd.2010.06.012
Type: Article
Description: Post print version of article may differ from published version. The definitive version is available through Elsevier at DOI: 10.1053/j.ajkd.2010.06.012
URI: http://hdl.handle.net/10027/7574
ISSN: 1523-6838
Sponsor: Sanjeev Akkina was supported by a research grant from the American Society of Transplantation and the National Institute of Diabetes and Digestive and Kidney Diseases, Award Number K23DK084121. Ajay Israni is a Robert Wood Johnson Foundation Physician Faculty Scholar. S. Joseph Kim is supported by the Clinician-Scientist Training Award, Canadian Institutes of Health Research.
Date Available in INDIGO: 2011-05-05
 

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