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Spectral-domain OCT peripapillary retinal nerve fibre layer thickness measurements in patients with stargardt disease

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Title: Spectral-domain OCT peripapillary retinal nerve fibre layer thickness measurements in patients with stargardt disease
Author(s): Genead, Mohamed A.; Fishman, Gerald A.; Anastasakis, Anastasios
Subject(s): peripapillary retinal nerve fibre layer defects Stargardt disease
Abstract: Aims To evaluate the presence of peripapillary retinal nerve fibre layer (RNFL) defects in patients with Stargardt disease by using spectral-domain optical coherence tomography (SD-OCT). Methods Fifty-two eyes of 27 patients with Stargardt disease underwent peripapillary RNFL thickness measurements using SD-OCT. Results Twenty-seven patients with Stargardt disease were enrolled. Their mean (6SD) age was 38.3 (14.7) years. Fourteen patients (51.9%) showed a thinning of the peripapillary RNFL in one or more quadrants in at least one eye, and four patients (14.8%) in both eyes. Five patients (18.5%) showed a thickening of the peripapillary RNFL in at least one eye, and four patients (14.8%) in both eyes. Conclusion This study demonstrated the presence of defects in the peripapillary RNFL thickness in patients with Stargardt disease by using SD-OCT. It would be clinically prudent that Stargardt patients considered for various treatment options be considered for RNFL thickness measurements.
Issue Date: 2010-10-08
Publisher: BMJ Publishing Group
Citation Info: Genead, M. A., Fishman, G. A., & Anastasakis, A. 2010. Spectral-domain OCT peripapillary retinal nerve fibre layer thickness measurements in patients with stargardt disease. British Journal of Ophthalmology. DOI: 10.1136/bjo.2010.189720
Type: Article
Description: Post print version of article may differ from published version. The definitive version is available through BMJ Publishing Group at DOI: 10.1136/bjo.2010.189720
URI: http://hdl.handle.net/10027/7596
ISSN: 1468-2079
Sponsor: Supported by funds from the Foundation Fighting Blindness, Owings Mills, Maryland; Grant Healthcare Foundation, Lake Forest, Illinois; NIH core grant EYO1792; and an unrestricted departmental grant from Research to Prevent Blindness.
Date Available in INDIGO: 2011-05-11
 

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