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Cystic Macular Edema on Spectral-Domain Optical Coherence Tomography in Choroideremia Patients without Cystic Changes on Fundus Examination

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Title: Cystic Macular Edema on Spectral-Domain Optical Coherence Tomography in Choroideremia Patients without Cystic Changes on Fundus Examination
Alternative Title: Cystic macular edema in choroideremia patients
Author(s): Genead, Mohamed A.; Fishman, Gerald A.
Subject(s): Choroideremia Cystic macular edema SD-OCT
Abstract: Purpose: To determine the prevalence of cystic macular edema (CME) in patients with choroideremia by using spectral-domain optical coherence tomography (SD-OCT). Methods: Sixteen patients affected with choroideremia were enrolled in the study. All patients underwent a complete eye examination. SD-OCT was performed using an OPKO spectral-domain OCT/SLO instrument. Results: The average age of the study patients was 44.0 ± 16.0 years (range, 13-63 years). Out of the 16 patients with choroideremia, 10 patients (62.5%) showed a degree of CME on SD-OCT testing in at least one eye, and 8 patients (50%) showed CME in both eyes. Conclusions: Because of its notable prevalence, it would seem prudent to screen choroideremia patients by SD-OCT for the possible presence of CME and to identify those amenable to future treatment strategies for their macular edema.
Issue Date: 2010-10-22
Publisher: Nature Publishing Group
Citation Info: Genead, Mohamed A., Fishman, Gerald A. 2010. Cystic Macular Edema on Spectral-Domain Optical Coherence Tomography in Choroideremia Patients without Cystic Changes on Fundus Examination. Eye 25: 84-90. DOI: 10.1038/eye.2010.157
Type: Article
Description: Post print version of article may differ from published version. The definitive version is available through Nature Publishing Group at DOI: 10.1038/eye.2010.157.
URI: http://hdl.handle.net/10027/7774
ISSN: 0950-222X
Sponsor: Supported by funds from the Foundation Fighting Blindness, Owings Mills, Maryland; Grant Healthcare Foundation, Lake Forest, Illinois; NIH core grant EYO1792; and an unrestricted departmental grant from Research to Prevent Blindness.
Date Available in INDIGO: 2011-05-27
 

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