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Progressive Resistance Exercise and Parkinson’s Disease: A Review of PotentialMechanisms

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Title: Progressive Resistance Exercise and Parkinson’s Disease: A Review of PotentialMechanisms
Author(s): David, Fabian J.; Rafferty, Miriam R.; Robichaud, Julie A.; Prodoehl, Janey; Kohrt, Wendy M.; Vaillancourt, David E.; Corcos, Daniel M.
Abstract: This paper reviews the therapeutically beneficial effects of progressive resistance exercise (PRE) on Parkinson’s disease (PD). First, this paper discusses the rationale for PRE in PD.Within the first section, the review discusses the central mechanisms that underlie bradykinesia and muscle weakness, highlights findings related to the central changes that accompany PRE in healthy individuals, and extends these findings to individuals with PD. It then illustrates the hypothesized positive effects of PRE on nigro-striatalthalamo- cortical activation and connectivity. Second, it reviews recent findings of the use of PRE in individuals with PD. Finally, knowledge gaps of using PRE on individuals with PD are discussed along with suggestions for future research.
Issue Date: 2012
Publisher: SAGE-Hindawi Access to Research
Citation Info: David, F. J., Rafferty, M. R., Robichaud, J. A., Prodoehl, J., Kohrt, W. M., Vaillancourt, D. E., & Corcos, D. M. 2012. Progressive resistance exercise and Parkinson's disease: a review of potential mechanisms. Parkinson’s Disease, 2012: 124527. DOI: 10.1155/2012/124527
Type: Article
Description: Copyright © 2012 Fabian J. David et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. DOI: 10.1155/2012/124527
ISSN: 2042-0080
Sponsor: This publication was made possible by the National Institutes of Health (5R01NS028127-16, 5T32MH067631-07).
Date Available in INDIGO: 2012-03-16

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