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Randomized controlled trial of primary care physician motivational interviewing versus brief advice to engage adolescents with an Internet-based depression prevention intervention: 6-month outcomes and predictors of improvement

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Title: Randomized controlled trial of primary care physician motivational interviewing versus brief advice to engage adolescents with an Internet-based depression prevention intervention: 6-month outcomes and predictors of improvement
Author(s): Hoek, Willemijn; Marko, Monika; Fogel, Joshua; Schuurmans, Josien; Gladstone, Tracy; Bradford, Nathan; Domanico, Rocco; Fagan, Blake; Bell, Carl; Reinecke, Mark A.; Van Voorhees, Benjamin W.
Abstract: We believe that primary care physicians could play a key role in engaging youth with a depression prevention intervention. We developed CATCH-IT (Competent Adulthood Transition with Cognitive Behavioral and Interpersonal Training), an adolescent Internet-based behavior change model. We conducted a randomized comparison of two approaches in engaging adolescents with the Internet intervention: primary care physician (PCP) motivational interview + CATCH-IT Internet program (MI) versus PCP brief advice + CATCH-IT Internet program (BA). Participants (N=84) were recruited by screening for risk of depression in 13 primary care practices. We compared depressive disorder outcomes between groups and within groups over 6 months and examined potential predictors and moderators of outcomes across both study arms. Depressive symptom scores declined from baseline to 6 weeks with these statistically significant reductions sustained at the 6 months follow-up in both groups. No significant interactions with treatment condition were found. However, by 6 months, the MI group demonstrated significantly fewer depressive episodes and reported less hopelessness as compared to the BA group. Hierarchical linear modeling regressions showed higher ratings of ease of use of the Internet program predicting lower depressive symptom levels over 6 months. In conclusion, a primary care/Internet-based intervention model among adolescents demonstrated reductions in depressed mood over 6 months and may result in fewer depressive episodes.
Issue Date: 2011-12
Publisher: Elsevier
Citation Info: Hoek, W., Marko, M., Fogel, J., Schuurmans, J., Gladstone, T., Bradford, N., Domanico, R., Fagan, B., Bell, C., Reinecke, M. A., & Van Voorhees, B. W. 2011. Randomized controlled trial of primary care physician motivational interviewing versus brief advice to engage adolescents with an Internet-based depression prevention intervention: 6-month outcomes and predictors of improvement. Translational Research, 158(6): 315-325. DOI: 10.1016/j.trsl.2011.07.006
Type: Article
Description: NOTICE: this is the author’s version of a work that was accepted for publication in Translational Research, The Journal of Laboratory and Clinical Medicine. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Translational Research, The Journal of Laboratory and Clinical Medicine, Vol 158, Issue 6, Dec 2011. DOI: 10.1016/j.trsl.2011.07.006
URI: http://hdl.handle.net/10027/8337
ISSN: 1931-5244
Sponsor: Supported by a NARSAD Young Investigator Award, Robert Wood Johnson Foundation Depression in Primary Care Value Grant and a career development award from the National Institutes of Mental Health (NIMH K-08 MH 072918-01A2) Clinical Trial Registry (clinicaltrials.gov): # NCT00152529 and NCT00145912
Date Available in INDIGO: 2012-05-27
 

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