posted on 2012-01-05, 00:00authored byVishal Sharma
This image represents a self-assembling tool for the sustained delivery of therapeutic agents. To form this particle, a drop of polymer solution is simply allowed to fall from the tip of a needle into a solution of similar viscosity. While the drop descends, it begins to turn in on itself to form inner channels made up of the outside solution. The end result is a doughnut like shape with spiral tunnels leading inside. This image was taken by a high speed camera that is capable of taking one million images per second. We are able to “freeze” the particle instantly using ultraviolet light so it becomes hard. The goal of this work is to deliver therapeutic agents, such as small drug molecules or proteins using this naturally occurring phenomenon. We can tailor our particle to contain multiple therapeutic agents by dissolving one into the polymer drop and one into the outside solution, which will go into the tunnels all by itself. It’s as if the particle has a mind all its own, leaving onlookers curious to see the limitless possibilities in which it can be used.
Funding
University of Illinois at Chicago Graduate College
History
Publisher Statement
Entry 2011 in The Image of Research, a competition for students in graduate or professional degree programs at UIC, sponsored by UIC's Graduate College and the University Library. Images of award recipients and honorable mention images on exhibition in the Richard J. Daley Library, April 13-May 30, 2011.