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A matter of perspective: Comparison of the characteristics of persons with HIV infection in the United States from the HIV outpatient study, medical monitoring project, and National HIV surveillance system

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posted on 12.09.2016, 00:00 by K. Buchacz, E. L. Frazier, H. I. Hall, R. Hart, P. Huang, D. Franklin, X. Hu, F. J. Palella, J. S. Chmiel, R. M. Novak, K. Wood, B. Yangco, C. Armon, J. T. Brooks, J. Skarbinski
Comparative analyses of the characteristics of persons living with HIV infection (PLWH) in the United States (US) captured in surveillance and other observational databases are few. To explore potential joint data use to guide HIV treatment and prevention in the US, we examined three CDC-funded data sources in 2012: the HIV Outpatient Study (HOPS), a multisite longitudinal cohort; the Medical Monitoring Project (MMP), a probability sample of PLWH receiving medical care; and the National HIV Surveillance System (NHSS), a surveillance system of all PLWH. Overall, data from 1,697 HOPS, 4,901 MMP, and 865,102 NHSS PLWH were analyzed. Compared with the MMP population, HOPS participants were more likely to be older, non-Hispanic/Latino white, not using injection drugs, insured, diagnosed with HIV before 2009, prescribed antiretroviral therapy, and to have most recent CD4+ T-lymphocyte cell count ≥500 cells/mm3 and most recent viral load test <200 copies/mL. The MMP population was demographically similar to all PLWH in NHSS, except it tended to be slightly older, HIV diagnosed more recently, and to have AIDS. Our comparative results provide an essential first step for combined epidemiologic data analyses to inform HIV care and prevention for PLWH in the US.

Funding

For the HOPS: Centers for Disease Control and Prevention (contract nos. 200-2001-00133, 200-2006-18797, and 200-2011-41872) For MMP: Centers for Disease Control and Prevention (Cooperative Agreement PS09-937). For NHSS: Centers for Disease Control and Prevention (Cooperative Agreement PS13-1302).

History

Publisher Statement

This is a copy of an article published in the Open AIDS Journal. © Buchacz et al. http://benthamopen.com/ABSTRACT/TOAIDJ-9-123.

Publisher

Bentham Open

Language

en_US

issn

1874-6136

Issue date

07/12/2015

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