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Considerations When Designing a Microbiome Study: Implications for Nursing Science

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journal contribution
posted on 09.04.2019 by Katherine A. Maki, Ana F. Diallo, Mark B. Lockwood, Alexis T. Franks, Stefan J. Green, Paule V. Joseph
Nurse scientists play an important role in studying complex relationships among human genetics, environmental factors, and the microbiome, all of which can contribute to human health and disease. Therefore, it is essential that they have the tools necessary to execute a successful microbiome research study. The purpose of this paper is to highlight important methodological factors for nurse scientists to consider when designing a microbiome study. In addition to considering factors that influence host-associated microbiomes (i.e., microorganisms associated with organisms such as humans, mice, and rats), this manuscript also highlights study designs and methods for microbiome analysis. Exemplars are presented from nurse scientists who have incorporated microbiome methods into their program of research. This review is intended to be a resource to guide nursing-focused microbiome research and highlight how study of the microbiome can be incorporated to answer research questions.

Funding

Support provided by the National Institute of Nursing Research (to PVJ, and Intramural Research Training Award to ATF); Office of Workforce Diversity, National Institutes of Health (NIH) to PVJ; Sigma Theta Tau International, Alpha Lambda Chamber to KAM; and University of Illinois at Chicago, College of Nursing, to KAM.

History

Publisher Statement

This is a copy of an article published in the Biological Research for Nursing. © 2015 SAGE Publications.

Citation

Maki, K. A., Diallo, A. F., Lockwood, M. B., Franks, A. T., Green, S. J., & Joseph, P. V. (2019). Considerations When Designing a Microbiome Study: Implications for Nursing Science. Biological Research for Nursing, 21(2), 125-141. doi:10.1177/1099800418811639

Publisher

SAGE Publications

Language

en

issn

1099-8004

Issue date

08/11/2018

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