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Drastic sensing enhancement using acoustic bubbles for surface-based microfluidic sensors

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posted on 19.06.2018 by A. De Vellis, D. Gritsenko, Y. Lin, Z. Wu, X. Zhang, Y. Pan, W. Xue, J. Xu
There is a high demand for ultrafast biosensors for industrial and public health applications. However, the performance of existing sensors is often limited by the slow mass transport process in traditional pressure-driven microfluidic devices. In this paper we show for the first time, that acoustic microbubbles trapped in prefabricated cavities in a micro-chamber are capable of enhancing fluid sample mixing that results in faster delivery of target species to the sensor surface. We demonstrate a drastic reduction of sensor response time (up to 21.3 fold) for surface-based nanosenors in presence of resonantly actuated microbubbles. The obtained results are valid in a wide pH (4-10) range and agree well with previous studies.

Funding

This research was supported by J. Xu’s start up fund at UIC.

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Citation

De Vellis, A., Gritsenko, D., Lin, Y., Wu, Z. P., Zhang, X., Pan, Y. Y., Xue, W. and Xu, J. Drastic sensing enhancement using acoustic bubbles for surface-based microfluidic sensors. Sensors and Actuators B-Chemical. 2017. 243: 298-302. 10.1016/j.snb.2016.11.098.

Publisher

Elsevier

Language

en_US

issn

0925-4005

Issue date

01/11/2016

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