Simulation of Drug Uptake in a Two Compartmental Fractional Model for a Biological System

2012-06-27T00:00:00Z (GMT) by Ivo Petráš Richard L. Magin
This paper presents a very effective numerical method for the solution of the two-compartmental pharmacokinetic model for oral drug administration. This model consists of a set of two fractional order differential equations which connect the two compartments. The rst compartment represents the gut while the second compartment corresponds to the drug concentration in the target tissue. For ease of computation, the numerical solution is also created as a Matlab function.