Successful longterm.pdf (172.7 kB)
0/0

Successful long-term thalidomide therapy for discoid lupus erythematosus-lichen planus overlap syndrome

Download (172.7 kB)
journal contribution
posted on 04.05.2016 by L. Zhang, S. Au, I.K. Aronson
Although thalidomide is a U.S. Food and Drug Admistration (FDA) approved medication for erythema nodosum leprosum and multiple myeloma, it has many off-label uses, including for discoid lupus erythematosus (DLE), Behçet’s disease, apththous ulcers in HIV patients, and prurigo nodularis. Herein, we present a patient with an overlap of discoid lupus erythematosus and lichen planus who was successfully treated with thalidomide for over 19 years without significant side effects. We propose that some of the most common side effects, including peripheral neuropathy, numbness, parasthesias, sedation, and constipation, can be avoided at lower doses, typically less than 100mg/day

Funding

None

History

Publisher Statement

This is a copy of an article published in the Dermatology Online Journal © 2014 University of California, Davis, ; Dermatology Online Journal is available online at:http://escholarship.org/uc/item/73r7492v

Publisher

University of California, Davis

issn

1087-2108

Issue date

01/10/2014

Exports

Categories

Exports