Li&McGinleyBiologicalSciences.jpg (479.89 kB)

mRNA Localization of ASXL2

Download (479.89 kB)
journal contribution
posted on 30.07.2019, 00:00 by Yanyang Li, Andrea L. McGinley
Congenital heart disease (CHD) is the most common birth defect. However, the etiology for the majority of CHD cases have been unknown. Our lab identified a chromatin factor, Additional Sex Combs-Like 2 (ASXL2), as a novel regulator of cardiovascular development. ASXL2 fetuses display congenital heart malformations. To support the notion that ASXL2 plays important roles in cardiovascular development, I conducted whole mount in situ hybridization experiment to examine the distribution of ASXL2 mRNA in mouse embryo at embryonic day 10.5. It resulted in a surprisingly beautiful pattern of high expression level of ASXL2 in the heart and somites. The image in the submission was captured by Andrea using a dissection microscope.

Categories

Keyword(s)

Funding

This exhibit competition is organized by the University of Illinois at Chicago Graduate College and the University Library.

History

Publisher Statement

Biological Sciences; Finalist; Copyright 2014, Yanyang Li & Andrea L. McGinley. Used with permission. For more information, contact the Graduate College at gradcoll@uic.edu

Language

en

Issue date

01/01/2014

Exports

Categories

Keyword(s)

Exports