A novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO.

Morales, Tiara G Pérez; Ratia, Kiira; Wang, Duo-Sheng; Gogos, Artemis; Driver, Tom; Federle, Michael

doi:10.25417/uic.19658169.v1

PepO JBC-2018-Pérez Morales.pdf (2.17 MB)

A novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO.

journal contribution

posted on 06.05.2022, 19:02 authored by Tiara G Pérez Morales, Kiira Ratia, Duo-Sheng Wang, Artemis Gogos, Tom DriverTom Driver, Michael FederleMichael Federle

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Funding

Mechanistic Dissection Of Pheromone-Dependent Regulation Of Group A Streptococcal Virulence | Funder: National Institutes of Health (National Institute of Allergy and Infectious Diseases) | Grant ID: R01AI091779

Molecular Mechanisms of Rgg Receptor Regulation by Pheromones and Inhibitors | Funder: Rutgers The State University of New Jersey | Grant ID: R01AI125452

History

Citation

Pérez Morales, T. G., Ratia, K., Wang, D. -S., Gogos, A., Bloem, L., Driver, T. G.Federle, M. J. (2018). A novel chemical inducer of Streptococcus quorum sensing acts by inhibiting the pheromone-degrading endopeptidase PepO. Journal of Biological Chemistry, 293(12), 4580-. https://doi.org/10.1074/jbc.aac118.002674