Computational Studies of the Effect of the S23D/S24D Troponin I Mutation
on Cardiac Troponin Structural Dynamics

Cheng, Y.H.; Lindert, S.; Kekenes-Huskey, P.; Rao, V.S.; Solaro, R.J.; Rosevear, P.R.; Amaro, R.

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Computational Studies of the Effect of the S23D/S24D Troponin I Mutation on Cardiac Troponin Structural Dynamics

journal contribution

posted on 2017-01-16, 00:00 authored by Y.H. Cheng, S. Lindert, P. Kekenes-Huskey, V.S. Rao, R.J. Solaro, P.R. Rosevear, R. Amaro

Cheng, Y. H., Lindert, S., Kekenes-Huskey, P., Rao, V. S., Solaro, R. J., Rosevear, P. R., Amaro, R., McCulloch, A. D., McCammon, J. A. and Regnier, M. Computational Studies of the Effect of the S23D/S24D Troponin I Mutation on Cardiac Troponin Structural Dynamics. Biophysical Journal. 2014. 107(7): 1675-1685. DOI:10.1016/j.bpj.2014.08.008.

Funding

This research was supported by NIH grants R01 HL-65497 and HL-11197 (M.R.), PO1 HL-062426 (R.J.S.), AHA 11POST7400069 (V.S.R.), and AHA 12POST11570005 (S.L.). Funding and support from the National Biomedical Computational Resource (NBCR) is provided through NIH grant P41 GM103426 to Y.C., S.L., and P.K.-H. Work by J.A.M.’s group is supported in part by the NSF, NIH, HHMI, and NSF Supercomputer Centers.

History

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Publisher

Biophysical Society (Elsevier-Cell Press)

issn

0006-3495

Issue date

2014-10-01

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