Maki_ConsiderationsMicrobiomeStudy_ImplicationsNursingScience.docx (688.58 kB)

Considerations When Designing a Microbiome Study: Implications for Nursing Science

Download (688.58 kB)
journal contribution
posted on 09.04.2019, 00:00 by Katherine A. Maki, Ana F. Diallo, Mark B. Lockwood, Alexis T. Franks, Stefan J. Green, Paule V. Joseph
Nurse scientists play an important role in studying complex relationships among human genetics, environmental factors, and the microbiome, all of which can contribute to human health and disease. Therefore, it is essential that they have the tools necessary to execute a successful microbiome research study. The purpose of this paper is to highlight important methodological factors for nurse scientists to consider when designing a microbiome study. In addition to considering factors that influence host-associated microbiomes (i.e., microorganisms associated with organisms such as humans, mice, and rats), this manuscript also highlights study designs and methods for microbiome analysis. Exemplars are presented from nurse scientists who have incorporated microbiome methods into their program of research. This review is intended to be a resource to guide nursing-focused microbiome research and highlight how study of the microbiome can be incorporated to answer research questions.


Support provided by the National Institute of Nursing Research (to PVJ, and Intramural Research Training Award to ATF); Office of Workforce Diversity, National Institutes of Health (NIH) to PVJ; Sigma Theta Tau International, Alpha Lambda Chamber to KAM; and University of Illinois at Chicago, College of Nursing, to KAM.


Publisher Statement

This is a copy of an article published in the Biological Research for Nursing. © 2015 SAGE Publications.


Maki, K. A., Diallo, A. F., Lockwood, M. B., Franks, A. T., Green, S. J., & Joseph, P. V. (2019). Considerations When Designing a Microbiome Study: Implications for Nursing Science. Biological Research for Nursing, 21(2), 125-141. doi:10.1177/1099800418811639


SAGE Publications





Issue date