posted on 2011-05-05, 00:00authored byDan V. Mihailescu, Avni Vora, Theodore Mazzone
Various alterations of lipid homeostasis have a significant role in the pathophysiology of the artherosclerotic process. The effects of usual lipid-lowering agents such as statins, fibrates, or niacin are well known, but other endocrine therapeutic agents could also affect the blood levels of various lipoproteins and, in turn, influence atheroma formation. In this review, we attempt to summarize the effect of several hormonal and non-hormonal endocrine agents on lipid metabolism, including insulin, thyroid hormone, sex hormones, glucocorticoids, growth hormone, and several anti-diabetic agents.
TM has received a grant from Takeda for research support as well as an honorarium from Abbott for consulting work. DVM and IV report no potential conflicts of interest relevant to this article.
The original publication is available at www.springerlink.com; DOI: 10.1007/s11883-010-0146-z