posted on 2012-08-20, 00:00authored byPrimal de Lanerolle, Leonid Serebryannyy
Actin and myosin are major components of the cell cytoskeleton, with structural and regulatory functions that impact many essential cellular processes. Actin and myosin were traditionally thought to function only in the cytoplasm. However, it is now well accepted that actin and multiple myosins are found in the nucleus. Increasing evidence on their functional roles has highlighted the importance of these proteins in the nuclear compartment.
Funding
Supported by a grant from the National Institutes of Health (R01GM080587) to PdeL.