Nuclear actin and myosins: Life without filaments

Actin and myosin are major components of the cell cytoskeleton, with structural and regulatory functions that impact many essential cellular processes. Actin and myosin were traditionally thought to function only in the cytoplasm. However, it is now well accepted that actin and multiple myosins are found in the nucleus. Increasing evidence on their functional roles has highlighted the importance of these proteins in the nuclear compartment.