Recent advances in transition metal-catalyzed N-atom transfer reactions of azides
journal contributionposted on 2011-08-31, 00:00 authored by Tom G. Driver
Transition metal-catalyzed N-atom transfer reactions of azides provide efficient ways to construct new carbon–nitrogen and sulfur–nitrogen bonds. These reactions are inherently green: no additive besides catalyst is needed to form the nitrenoid reactive intermediate, and the by-product of the reaction is environmentally benign N2 gas. As such, azides can be useful precursors for transition metal-catalyzed N-atom transfer to sulfides, olefins and C–H bonds. These methods offer competitive selectivities and comparable substrate scope as alternative processes to generate metal nitrenoids.
The National Institutes of Health NIGMS (R01GM084945), Petroleum Research Fund administered by the American Chemical Society (46850-G1), and the University of Illinois at Chicago are acknowledged for their generous support of our research program.
Publisher StatementThe definitive version is available through Royal Society of Chemistry at DOI: 10.1039/c005219c
PublisherRoyal Society of Chemistry