Recommendations for Diagnosis and Prevention.pdf (552.37 kB)
Recommendations for Diagnosis and Prevention of Cytomegalovirus-Associated Necrotizing Enterocolitis in Breast-Fed Preterm Infants.
journal contributionposted on 2023-04-17, 16:41 authored by Jennifer PhamJennifer Pham, Allison F Dahlgren, Phornphat Rasamimari
We present the case of a breast-fed preterm infant with postnatally acquired cytomegalovirus (CMV) and severe necrotizing enterocolitis (NEC) associated with CMV. The infant had persistent severe thrombocytopenia with clinical deterioration despite multiple platelet transfusions and maximal medical treatment. Surgical intervention was not feasible owing to the instability of the infant's condition. Upon identification of CMV in urine, intravenous ganciclovir was initiated with significant clinical improvement. We also present a literature review of cases of CMV-related NEC or other gastrointestinal complications in preterm and term infants.
CitationPham, J. T., Dahlgren, A. F.Rasamimari, P. (2022). Recommendations for Diagnosis and Prevention of Cytomegalovirus-Associated Necrotizing Enterocolitis in Breast-Fed Preterm Infants. The Journal of Pediatric Pharmacology and Therapeutics, 27(2), 180-191. https://doi.org/10.5863/1551-6776-27.2.180
PublisherPediatric Pharmacy Advocacy Group
CategoriesNo categories selected
Infant MortalityPatient SafetyBreast CancerPerinatal Period - Conditions Originating in Perinatal PeriodPreterm, Low Birth Weight and Health of the NewbornClinical ResearchPediatricPreventionCancer4.1 Discovery and preclinical testing of markers and technologiesCardiovascularbreast milkcytomegalovirusganciclovirnecrotizing enterocolitispreterm infant