Regio- and steroselectivity....pdf (797.98 kB)
Regio- and stereoselectivity in the concatenated enyne cross metathesis-metallotropic 1,3 -shift of terminal 1,3-diyne.
journal contributionposted on 2018-01-09, 00:00 authored by K.-P. Wang, E.J. Cho, S.Y. Yun, J.Y. Rheea, D. Lee
Enyne cross metathesis of terminal 1,3-diynes with various alkenes afforded two products of distinctive connectivity, as the result of a uniform mode of initiation but different modes of termination events with or without metallotropic [1,3]-shift. Steric and electronic factors of the substituents on the 1,3-diynes play an important role in controlling the metallotropic [1,3]-shift of the propagating alkylidene intermediates and their regioselective trapping to the final products. © 2013 Elsevier Ltd. All rights reserved.