Spindle cell sarcomatoid carcinoma of the trachea.pdf (1.46 MB)
Spindle cell sarcomatoid carcinoma of the trachea: first case report of surgical resection
journal contribution
posted on 2016-09-14, 00:00 authored by Juan P. Gurria, David M. De Acosta, Niloufar Hafezi, Eman B. Yousif, Ehab AlAmeer, Richard C. AndersonBackground: Primary malignant tracheal tumors are rare, accounting for approximately 0.2 % of respiratory tract
tumors yearly, with squamous cell carcinomas and adenoid cystic carcinomas accounting for two-thirds of these
cases. Sarcomatoid carcinomas are a group of poorly differentiated non-small cell lung carcinomas containing a
component of sarcoma or sarcoma-like (spindle and/or giant cell) differentiation, categorized into five morphologic
subgroups. Spindle cell sarcomatoid carcinoma is a rare variant of sarcomatoid carcinomas, consisting of only
spindle-shaped tumor cells. Only one other case has been reported as a primary tracheal tumor.
Case presentation: We present a 75-year-old male, having progressive dyspnea and cough, with a spindle cell
sarcomatoid carcinoma tumor visualized on chest computed tomography scan and confirmed with biopsy.
Conclusions: Due to its low incidence, knowledge of treatment methods, prognostic factors, and etiology is
limited thus approaches to eradication have widely varied. We are reporting the second published case of spindle cell
sarcomatoid carcinoma of the trachea and the first reported successful outcome of definitive treatment with tracheal
resection.
Funding
The Research Open Access Publishing (ROAAP) Fund of the University of Illinois at Chicago, for financial support towards the open access publishing fee for this article.
History
Publisher Statement
This is a copy of an article published in the Journal of Cardiothoracic. © 2016 The Author(s).Publisher
BioMed CentralLanguage
- en_US
issn
1749-8090Issue date
2016-08-05Usage metrics
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