Synthesis of substituted isatins
journal contributionposted on 2013-12-05, 00:00 authored by Larry L. Klein, Michael D. Tufano
Isatins are valuable intermediates for heterocyclic chemistry. Most of the common methods for their production are less than adequate when the number and lipophilicity of substituents on the targeted isatin are increased. Our group desired such molecules and identified an alternative method for their production.
Publisher StatementNOTICE: This is the author’s version of a work that was accepted for publication in Tetrahedron Letters. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Tetrahedron Letters, [Vol 54, Issue 8, 2013] DOI: 10.1016/j.tetlet.2012.12.035