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The Effects of the BAILAMOS Dance Program on Brain Functional Connectivity of Older Latinos: An Exploratory Study
journal contributionposted on 2022-04-06, 16:50 authored by Guilherme Moraes Balbim, Olusola AjiloreOlusola Ajilore, Melissa LamarMelissa Lamar, Kirk Erickson, Susan Aguiñaga, Eduardo BustamanteEduardo Bustamante, David MarquezDavid Marquez
Abstract Compared to non-Latinos whites, older Latinos are at higher risk of cognitive impairment and engage in less leisure-time physical activity (PA). Resting-state brain functional connectivity (FC) is a putative biomarker for age-related cognitive decline. PA plays a role in FC of brain networks associated with cognitive decline. Objective: Investigate the effects of the BAILAMOS™ dance program on FC in three brain networks associated with age-related cognitive decline (Default Mode [DMN], Frontoparietal [FPN], and Salience [SAL] networks). Methods: Single-group pre-post design. Ten cognitively intact older Latinos participated in the four-month (2x/week for 60min) BAILAMOS™ dance program with four Latin dance styles. MRI was obtained pre- and post-intervention. FC was analyzed using the resting-state fMRI toolbox (CONN) via pairwise BOLD signal correlations and then converted into z-scores. We performed dependent t-tests, computed Cohen’s d and 95%CI for p < 0.05. Results: Within-FPN FC significantly increased (t(9) = 2.35, p = 0.043, d = 0.70) from pre (M=0.49±0.15) to post-intervention (M=0.59±0.13). In the DMN, we observed moderate effect size changes in the ratio of the FC between-networks by the FC within-networks (Mdiff = 0.10; 95%CI = -0.01; 0.21, p = 0.08, d = 0.64). Conclusions: The BAILAMOS™ program increased within-FPN FC, which is a cognitive-control network related to adaptive control and flexibility. Moderate changes between- vs. within-DMN FC suggest BAILAMOS™ also increased whole-brain DMN integration. Taken together, results might signal that Latin dance can combat the disruption of FC between the DMN and other networks, and within-FPN, which are associated with cognitive decline.