JALHH germline review 2016 revised lab.pdf (341.76 kB)
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The evolution of insect germline specification strategies

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journal contribution
posted on 02.02.2018, 00:00 authored by H. Quan, J.A. Lynch
The establishment of the germline is essential for sexually reproducing organisms. In animals, there are two major strategies to specify the germline: maternal provision and zygotic induction. The molecular basis of the maternal provision mode has been well characterized in several model organisms (fly, frog, fish, and nematode), while that of the zygotic induction mode has mainly been studied in mammalian models such as the mouse. Shifts in germline determination modes occur unexpectedly frequently and many such shifts have occurred several times among insects. Given their general tractability and rapidly increasing genomic and genetic tools applicable to many species, the insects present a uniquely powerful model system for understanding major transitions in reproductive strategies, and developmental processes in general.


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Publisher Statement

NOTICE: This is the author’s version of a work that was accepted for publication in Current Opinion in Insect Science. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Current Opinion in Insect Science 13 (2016): 99-105. DOI: 10.1016/j.cois.2016.02.013







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