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Time-gated luminescence microscopy with responsive nonmetal probes for mapping activity of protein kinases in living cells

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posted on 2013-12-06, 00:00 authored by Angela Vaasa, Kadri Ligi, Shabnam Mohandessi, Erki Enkvist, Asko Uri, Lawrence W. Miller
A photoluminescence probe ARC-1185, possessing both high affinity towards basophilic protein kinases (PKs) and microsecond-scale luminescence lifetime when associated with a kinase, was used for the mapping of ARC-1185-PK complexes in living cells with time-gated luminescence microscopy.

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Post print version of article may differ from published version. The definitive version is available through Royal Society of Chemistry at DOI: 10.1039/c2cc33565d

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Royal Society of Chemistry

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  • en_US

issn

1359-7345

Issue date

2012-07-01

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