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Treating posttraumatic stress disorder at home in a single week using 1‐week virtual massed cognitive processing therapy

journal contribution
posted on 2022-11-11, 22:23 authored by Philip Held, Merdijana Kovacevic, Kelsey Petrey, Enya A Meade, Sarah Pridgen, Mauricio Montes, Brianna Werner, Michelle L Miller, Dale L Smith, Debra Kaysen, Niranjan S Karnik
Posttraumatic stress disorder (PTSD) treatments are increasingly delivered in massed formats and have shown comparable results to standard, weekly treatment. To date, massed cognitive processing therapy (CPT), delivered daily, has been delivered primarily in combination with adjunctive services and among veteran populations, but it has not been rigorously evaluated as a standalone intervention. The present study evaluated 1-week massed CPT delivered virtually (i.e., via telehealth) to a community sample of trauma-exposed individuals (N = 24). Using a single-arm open-label design, participants received CPT twice per day for 5 days. The results indicated that most participants completed treatment (n = 23, 95.8%), and no adverse events were reported. Participants exhibited large reductions in clinician-rated, d = 2.01, and self-reported PTSD symptoms, d = 2.55, as well as self-reported depressive symptoms, d = 1.46. On average, participants reported a 5-point PTSD symptom reduction and 1-point reduction in depressive symptoms for each treatment day. Reductions in PTSD and depressive symptoms were maintained at 3-month follow-up. Overall, 1-week massed CPT delivered virtually was shown to be feasible and to result in rapid symptom reductions that were sustained over time. Virtual massed CPT has the potential to increase access to effective treatments and help trauma survivors restore aspects of their lives in short amounts of time.


Great Lakes Node of the Drug Abuse Clinical Trials Network | Funder: National Institutes of Health (National Institute on Drug Abuse) | Grant ID: UG1DA049467

Employing eSBI in a Community-based HIV Testing Environment for At-risk Youth | Funder: National Institute on Drug Abuse | Grant ID: R01DA041071



Held, P., Kovacevic, M., Petrey, K., Meade, E. A., Pridgen, S., Montes, M., Werner, B., Miller, M. L., Smith, D. L., Kaysen, D.Karnik, N. S. (2022). Treating posttraumatic stress disorder at home in a single week using 1‐week virtual massed cognitive processing therapy. Journal of Traumatic Stress, 35(4), 1215-1225.




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