Allene and Alkyne: Development of Cycloaddition Reactions and Application to Natural Product Synthesis
thesisposted on 2021-08-01, 00:00 authored by Anh Duc Le
This thesis consists of two main parts, Part I and Part II. The four chapters in Part I cover various reactions of allene. The special structure containing three consecutive unsaturated carbons allows allene to participate in various cycloaddition reactions with multiple reacting counterparts, furnishing diverse products including multicyclic carbon framework. Part II describes the applications of cycloaddition reactions of allene in total synthesis of natural product selaginpulvilin A.