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Building Better Blood Vessels: Application of Endothelial Transcription Factors to Treat Ischemic Disease

thesis
posted on 01.05.2021, 00:00 by James S Hyun
Chronic vascular diseases are the leading causes of mortality and morbidity in the world. With no known effective therapies on the market, understanding the predominant vascular responses to ischemia can potentially lead to effective therapies to combat this global health issue. We investigated key developmental transcription factors important for endothelial development and angiogenesis. We further looked to mimic aspects of vasculogenesis and arterial specification to develop new therapies to enhance neovascularization.

History

Advisor

Malik, AsrarPajcini, Kostandin

Chair

Malik, Asrar

Department

Pharmacology

Degree Grantor

University of Illinois at Chicago

Degree Level

Doctoral

Degree name

PhD, Doctor of Philosophy

Committee Member

Karginov, Andrei Tiruppathi, Chinnaswamy Lee, Monica

Submitted date

May 2021

Thesis type

application/pdf

Language

en

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