University of Illinois Chicago
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Natural Products with Biological Activities from Freshwater Cyanobacteria

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posted on 2017-07-22, 00:00 authored by Shangwen Luo
In this study, bioassay-guided fractionation was utilized to find novel secondary metabolites from cultured and field collected freshwater cyanobacteria. The structures of these new compounds were elucidated using HRESIMS, 1D/2D NMR, QTOF MS/MS, CD spectroscopy, chemical synthesis, and advanced Marfey’s analysis. These new secondary metabolites were evaluated for their antiproliferative, antimicrobial, antifungal and protease inhibiting activities.

History

Language

  • en

Advisor

Orjala, Jimmy

Department

Medicinal Chemistry and Pharmacognosy

Degree Grantor

University of Illinois at Chicago

Degree Level

  • Doctoral

Committee Member

Swanson, Steven M. Murphy, Brian T. Che, Chun-Tao Johnson, Jeremy J.

Submitted date

2015-05

Issue date

2015-07-21

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    Keywords

    CyanobacteriaLipopeptideCyclophaneNatural ProductsSecondary Metabolites

    Licence

    In Copyright

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