Natural Products with Biological Activities from Freshwater Cyanobacteria

In this study, bioassay-guided fractionation was utilized to find novel secondary metabolites from cultured and field collected freshwater cyanobacteria. The structures of these new compounds were elucidated using HRESIMS, 1D/2D NMR, QTOF MS/MS, CD spectroscopy, chemical synthesis, and advanced Marfey’s analysis. These new secondary metabolites were evaluated for their antiproliferative, antimicrobial, antifungal and protease inhibiting activities.