Optical Detection of Immunoglobulin E
thesisposted on 21.02.2013, 00:00 by Saadia Ranginwala
Aptamers have a wide range of applications in clinical applications. A review of aptamers, and their applications has been given. Immunoglobulin E is an antibody associated with allergic reactions, and immune deficiency related diseases. The aptamer for Immunoglobulin E was found in the literature. An optical sensor, for the detection of Immunoglobulin E, was designed. The aptamer for Immunoglobulin was the main part of the designed sensor. Raman spectroscopy provides the molecular fingerprint of biological molecules. Substrate Enhanced Raman Spectroscopy was performed in order to obtain a molecular fingerprint of the Immunoglobulin E aptamer.