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Phytochemical Investigation of a Traditional West African Ethnomedicinal Plant, Icacina trichantha

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thesis
posted on 01.08.2020, 00:00 by Brian Chen Guo
In this dissertation, a phytochemical analysis of a West African ethnomedicinal plant, Icacina trichantha, was carried out. A bioassay-guided fractionation approach was applied to find novel secondary metabolites from plant extract material. The structures of these new compounds were elucidated using spectroscopic methods including HRESIMS, NMR, CD spectroscopy, and x-ray crystallography. The isolated natural products were evaluated for their cytotoxic and anti-germination activities.

History

Advisor

Che, Chun-Tao

Chair

Che, Chun-Tao

Department

Pharmaceutical Sciences

Degree Grantor

University of Illinois at Chicago

Degree Level

Doctoral

Degree name

PhD, Doctor of Philosophy

Committee Member

Burdette, Joanna E Johnson, Jeremy J Mahady, Gail B Murphy, Brian T Wardrop, Duncan

Submitted date

August 2020

Thesis type

application/pdf

Language

en

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