GUO-DISSERTATION-2020.pdf (5.87 MB)
Phytochemical Investigation of a Traditional West African Ethnomedicinal Plant, Icacina trichantha
thesisposted on 2020-08-01, 00:00 authored by Brian Chen Guo
In this dissertation, a phytochemical analysis of a West African ethnomedicinal plant, Icacina trichantha, was carried out. A bioassay-guided fractionation approach was applied to find novel secondary metabolites from plant extract material. The structures of these new compounds were elucidated using spectroscopic methods including HRESIMS, NMR, CD spectroscopy, and x-ray crystallography. The isolated natural products were evaluated for their cytotoxic and anti-germination activities.
Degree GrantorUniversity of Illinois at Chicago
Degree namePhD, Doctor of Philosophy
Committee MemberBurdette, Joanna E Johnson, Jeremy J Mahady, Gail B Murphy, Brian T Wardrop, Duncan
Submitted dateAugust 2020