The Development of New Methods to Streamline Heterocycle Synthesis

A series of new methods of C-N bond formation using azide or nitro group as nitrogen atom source were developed. The synthetic utility of these methods were demonstrated. Control experiments were performed for mechanistic study. Synthesis and characterization of new N-heteroheptacenes for solution-based organic field effect transistor were accomplished. A new and efficient synthetic route to FTY-720 phosphonate analogues was established.