Chemistry

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Phage ELISA for testing the specificities of TA8-derived variants and the alignment of their variable loop sequences.

Phage ELISA for testing the specificities of TA8-derived variants and the alignment of their variable loop sequences.

figure posted on 2016-01-18

Alanine scanning and design of the secondary library.

Alanine scanning and design of the secondary library.

figure posted on 2016-01-18

Mapping the binding location of two monobodies in comparison to a peptide ligand.

Mapping the binding location of two monobodies in comparison to a peptide ligand.

figure posted on 2016-01-18

Characterization of the specificity and affinity of TA8 monobody.

Characterization of the specificity and affinity of TA8 monobody.

figure posted on 2016-01-18

Characterization of two TA8-derived variants, 2H7 and 3C12.

Characterization of two TA8-derived variants, 2H7 and 3C12.

figure posted on 2016-01-18

Directed Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase

Directed Evolution of a Highly Specific FN3 Monobody to the SH3 Domain of Human Lyn Tyrosine Kinase

dataset posted on 2016-01-18

Evolutionary relatedness of Src family kinases (SFKs) and their common architecture.

Evolutionary relatedness of Src family kinases (SFKs) and their common architecture.

figure posted on 2016-01-18

Enzyme-linked binding assay (ELBA) for testing specificities of three FN3 monobodies and sequence alignment of their variable loops.

Enzyme-linked binding assay (ELBA) for testing specificities of three FN3 monobodies and sequence alignment of their variable loops.

figure posted on 2016-01-18

Pull-down of endogenous Lyn from human cells.

Pull-down of endogenous Lyn from human cells.

figure posted on 2016-01-18

The 2H7 monobody did not perturb the kinase activity of Lyn.

The 2H7 monobody did not perturb the kinase activity of Lyn.

figure posted on 2016-01-18

Two-dimensional cell model.

Two-dimensional cell model.

figure posted on 2015-05-14

Data Structure.

Data Structure.

figure posted on 2015-05-14

Tension force and pressure.

Tension force and pressure.

figure posted on 2015-05-14

Change in Volume.

Change in Volume.

figure posted on 2015-05-14

Cell geometry.

figure posted on 2015-05-14

Topological primitives.

Topological primitives.

figure posted on 2015-05-14

Visualization of the growth of tissue from 2 to 4,000 cells.

Visualization of the growth of tissue from 2 to 4,000 cells.

figure posted on 2015-05-14

Model of tissue development starting from a single cell.

Model of tissue development starting from a single cell.

figure posted on 2015-05-14

Fusion of cells and tissues.

Fusion of cells and tissues.

figure posted on 2015-05-14

Apoptosis of a peripheral cell.

Apoptosis of a peripheral cell.

figure posted on 2015-05-14

Bristles.

figure posted on 2015-05-14

Aggregation of Bristles.

Aggregation of Bristles.

figure posted on 2015-05-14

Bristle Plotting Puzzle.

Bristle Plotting Puzzle.

figure posted on 2015-05-14

Steady state spatial gradients of <i>Dl</i> of different diffusion rates.

Steady state spatial gradients of Dl of different diffusion rates.

figure posted on 2015-05-14

Relationship between stripe width and Inhibition Radius.

Relationship between stripe width and Inhibition Radius.

figure posted on 2015-05-14

The degree of alignment by an index ϱ.

The degree of alignment by an index ϱ.

figure posted on 2015-05-14

Model of feedback circuits for tissue size control.

Model of feedback circuits for tissue size control.

figure posted on 2015-05-14

Effects of different inhibition ranges of secreted factors in negative feedback loop to stem cells on tissue size control.

Effects of different inhibition ranges of secreted factors in negative feedback loop to stem cells on tissue size control.

figure posted on 2015-05-14

Effects of inhibitions to stem cell symmetric and asymmetric divisions.

Effects of inhibitions to stem cell symmetric and asymmetric divisions.

figure posted on 2015-05-14

Butterfly Scales with Inhibition Field radius of 2 cells.

Butterfly Scales with Inhibition Field radius of 2 cells.

figure posted on 2015-05-14

Comparisons to existing methods.

dataset posted on 2015-05-14

Algorithm 1. UpdateCellPattern (V(t), Δ (t), Δη(t), σ, k).

dataset posted on 2015-05-14

Simulation results for“Pre-destined”, “Lateral inhibition”, “Lateral inhibition with stripes”, “Inhibition Field”, and“Inhibition Field with Stripes”models.

dataset posted on 2015-05-14

Mechanical Model of Geometric Cell and Topological Algorithm for Cell Dynamics from Single-Cell to Formation of Monolayered Tissues with Pattern

Mechanical Model of Geometric Cell and Topological Algorithm for Cell Dynamics from Single-Cell to Formation of Monolayered Tissues with Pattern

dataset posted on 2015-05-14

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways

dataset posted on 2015-05-08

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways - Fig 1

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways - Fig 1

figure posted on 2015-05-08

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways - Fig 2

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways - Fig 2

figure posted on 2015-05-08

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways - Fig 3

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways - Fig 3

figure posted on 2015-05-08

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways - Fig 4

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways - Fig 4

figure posted on 2015-05-08

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways - Fig 5

Mechanisms of Intestinal Serotonin Transporter (SERT) Upregulation by TGF-β1 Induced Non-Smad Pathways - Fig 5

figure posted on 2015-05-08