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dc.contributor.authorPetiwala, Sakina M.
dc.contributor.authorPuthenveetil, Angela G.
dc.contributor.authorJohnson, Jeremy J.
dc.date.accessioned2013-12-05T19:53:15Z
dc.date.available2013-12-05T19:53:15Z
dc.date.issued2013-03
dc.identifier.bibliographicCitationPetiwala SM, Puthenveetil AG, Johnson JJ. Polyphenols from the Mediterranean herb rosemary (Rosmarinus officinalis) for prostate cancer.Frontiers in Pharmacology. 2013;4:29. doi: 10.3389/fphar.2013.00029.en_US
dc.identifier.issn1663-9812
dc.identifier.urihttp://hdl.handle.net/10027/10825
dc.descriptionThis Document is Protected by copyright and was first published by Frontiers. All rights reserved. It is reproduced with permission. © 2013 by Frontiers Research Foundation, Frontiers in Pharmacology.en_US
dc.description.abstractThe Mediterranean diet is rich in fruits and vegetables and has been associated with a variety of health benefits including cancer prevention. One aspect of the diet that has not received enough attention is Mediterranean herbs. Specifically, rosemary and its polyphenolic diterpenes (carnosic acid and carnosol) are known to possess anti-oxidant activity that may be beneficial for cancer control. Herein, we describe the in vitro and in vivo studies carried out towards understanding the molecular mechanisms of carnosic acid and carnosol leading to inhibition of prostate cancer. The reported findings suggest that these polyphenols target multiple signaling pathways involved in cell cycle modulation and apoptosis. Further work is required to understand its potential for health promotion and potential drug discovery for prostate cancer chemoprevention.en_US
dc.description.sponsorshipAspects of this work was supported by the American Cancer Society RSG CNE - 122480 (To Jeremy J. Johnson)en_US
dc.language.isoen_USen_US
dc.publisherFrontiers Research Foundationen_US
dc.subjectcarnosic aciden_US
dc.subjectprostate canceren_US
dc.subjectrosemary extracten_US
dc.subjectcarnosolen_US
dc.subjectditerpeneen_US
dc.titlePolyphenols from the Mediterranean herb rosemary (Rosmarinus officinalis) for prostate canceren_US
dc.typeArticleen_US


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