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dc.contributor.authorPearson, Ryan M.
dc.contributor.authorSunoqrot, Suhair
dc.contributor.authorHsu, Hao-jui
dc.contributor.authorBae, Jin Woo
dc.contributor.authorHong, Seungpyo
dc.date.accessioned2014-03-13T02:54:41Z
dc.date.available2014-03-13T02:54:41Z
dc.date.issued2012-08
dc.identifier.bibliographicCitationPearson RM, Sunoqrot S, Hsu HJ, Bae JW, Hong S. Dendritic nanoparticles: the next generation of nanocarriers? Therapeutic Delivery. 2012 Aug;3(8):941-59. 10.4155/TDE.12.76en_US
dc.identifier.issn2041-5990
dc.identifier.other10.4155/TDE.12.76
dc.identifier.urihttp://hdl.handle.net/10027/11306
dc.descriptionAccording to the guidelines provided by the publisher, this article is the pre-reviewed submitted manuscript to Therapeutic Delivery and does not incorporate adjustments to the content after peer reviewing. The citation for the published work is: R. M. Pearson, S. Sunoqrot, H.-j. Hsu, J. W. Bae, S. Hong, Therapeutic Delivery 3, 941 (2012).en_US
dc.description.abstractDendritic polymers have attracted a great deal of scientific interests due to their well-defined unique structure and capability to be multifunctionalized. Here we present a comprehensive overview of various dendrimer-based nanoparticles that are currently being investigated for drug delivery and diagnostics applications. Through a critical review of the old and new dendritic designs, we highlight the advantages and disadvantages of these systems and their structure- biological property relationships. This paper also focuses on the major challenges facing the clinical translation of these nanodevices, and how these challenges are being (or should be) addressed, which will greatly benefit the overall progress of dendrimer-based technologies for theranostics.en_US
dc.description.sponsorshipThis work has been supported by National Science Foundation under grant # CBET-0931472, Susan G Komen Foundation under grant # KG100713, and University of Illinois Foundation. RM Pearson was partially supported by a graduate fellowship from the American Foundation for Pharmaceutical Education.en_US
dc.publisherFuture Science Ltden_US
dc.subjectDendrimersen_US
dc.subjectNanoparticlesen_US
dc.subjectDendron micellesen_US
dc.subjectNanotechnologyen_US
dc.subjectdrug deliveryen_US
dc.subjectMultivalent Bindingen_US
dc.subjectnanocarrieren_US
dc.subjectpolymeren_US
dc.titleDendritic Nanoparticles: The next generation of nanocarriers?en_US
dc.typeArticleen_US


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