Browsing Microbiology and Immunology, Department of by Author "Vasu, Chenthamarakshan"
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IL-1β promotes TGF-β1 and IL-2 dependent Foxp3 expression in regulatory T cells
Ganesh, Balaji B.; Bhattacharya, Palash; Gopisetty, Anupama; Sheng, Jianrong; Vasu, Chenthamarakshan; Prabhakar, Bellur S. (Public Library of Science, 2011-07-11)Earlier, we have shown that GM-CSF-exposed CD8α- DCs that express low levels of pro-inflammatory cytokines IL-12 and IL-1β can induce Foxp3+ Tregs leading to suppression of autoimmunity. Here, we examined the differential ... -
IL-1β Promotes TGF-β1 and IL-2 Dependent Foxp3 Expression in Regulatory T Cells
Ganesh, Balaji B.; Bhattacharya, Palash; Gopisetty, Anupama; Sheng, Jianrong; Vasu, Chenthamarakshan; Prabhakar, Bellur S. (Public Library of Science, 2011-07-11)Earlier, we have shown that GM-CSF-exposed CD8a2 DCs that express low levels of pro-inflammatory cytokines IL-12 and IL-1b can induce Foxp3+ Tregs leading to suppression of autoimmunity. Here, we examined the differential ...