Now showing items 1-6 of 6
High-Dose Human Milk Feedings Decrease Oxidative Stress in Premature Infant
Background: Premature infants are susceptible to oxidative stress, increasing the risk of serious morbidities. High-dose human milk (HM) feedings decrease morbidity risks and may reduce oxidative stress in this population. ...
Increased Adiposity, Dysregulated Glucose Metabolism and Systemic Inflammation in Galectin-3 KO Mice
(Public Library of Science, 2013-02)
Obesity and type 2 diabetes are associated with increased production of Galectin-3 (Gal-3), a protein that modulates inflammation and clearance of glucose adducts. We used Lean and Diet-induced Obese (DIO) WT and Gal-3 KO ...
Rosiglitazone Improves Survival and Hastens Recovery from Pancreatic Inflammation in Obese Mice
(Public Library of Science, 2012-07)
Obesity increases severity of acute pancreatitis (AP) by unclear mechanisms. We investigated the effect of the PPAR-gamma agonist rosiglitazone (RGZ, 0.01% in the diet) on severity of AP induced by administration of IL-12+ ...
Hematological and acute-phase responses to diet-induced obesity in IL-6 KO mice
Obesity is associated with chronic inflammation and elevated levels of IL-6. The role of IL-6 in induction of acute-phase proteins and modulation of haematological responses has been demonstrated in models of inflammation ...
Increased Adiposity in Annexin A1-Deficient Mice
(PLoS One, 2013-12)
Production of Annexin A1 (ANXA1), a protein that mediates the anti-inflammatory action of glucocorticoids, is altered in obesity, but its role in modulation of adiposity has not yet been investigated. The objective of this ...
Digested Early Preterm Human Milk Suppresses Tumor Necrosis Factor-induced Inflammation and Cytotoxicity in Intestinal Epithelial Cells
(Lippincott, Williams & Wilkins, 2018-06)
OBJECTIVES: The aim of this study was to determine the effect of digested whole human milk (HM; first sample available after birth from mothers of premature infants) on inflammation, oxidative stress, and cytotoxicity in ...