Now showing items 56-75 of 105

    • Making dispersal syndromes and networks useful in tropical conservation and restoration 

      Howe, Henry F. (Elsevier, 2016-04-01)
      Dispersal syndromes and networks must be used cautiously in conserving and restoring seed-dispersal processes. In many tropical forests most tree and shrub species require dispersal by animals for local persistence and for ...
    • Making Sense of Hardy-Weinberg Equilibrium 

      Smith, MU; Baldwin, JT (University of California Press, 2015)
      A useful approach to answering the Next Generation Science Standards’ call for teaching students to demonstrate understanding using mathematical representations is use of the Hardy-Weinberg equilibrium (H-W eq). This article ...
    • Membrane Penetration by Synaptotagmin Is Required for Coupling Calcium Binding to Vesicle Fusion In Vivo 

      Paddock, Brie E.; Wang, Zhao; Biela, Laurie M.; Chen, Kaiyun; Getzy, Michael D.; Striegel, Amelia; Richmond, Janet E.; Chapman, Edwin R.; Featherstone, David E.; Reist, Noreen E. (Society for Neuroscience, 2011-02-09)
      The vesicle protein synaptotagmin I is the Ca2+ sensor that triggers fast, synchronous release of neurotransmitter. Specifically, Ca2+ binding by the C2B domain of synaptotagmin is required at intact synapses, yet the ...
    • Methods for cell-attached capacitance measurements in mouse adrenal chromaffin cell. 

      Varga, K.T.; Jiang, Z.; Gong, L.W. (Journal of Visualized Experiments, 2014-10-22)
      Neuronal transmission is an integral part of cellular communication within the brain. Depolarization of the presynaptic membrane leads to vesicle fusion known as exocytosis that mediates synaptic transmission. Subsequent ...
    • MiR-106a inhibits glioma cell growth by targeting E2F1 independent of p53 status 

      Yang, Guang; Zhang, Ruyou; Chen, Xiaofeng; Mu, Yulong; Ai, Jing; Shi, Chen; Liu, Yaohua; Shi, Changbin; Sun, Lihua; Rainov, Nikolai G.; Li, Hulun; Yang, Baofeng; Zhao, Shiguang (Springer Verlag, 2011-06-09)
      MicroRNAs are single-stranded small non-coding RNA molecules which regulate mammalian cell growth, differentiation, and apoptosis by altering the expression of other genes and play a role in tumor genesis and progression. ...
    • Modulation of Extracellular Proton Fluxes from Retinal Horizontal Cells of the Catfish by Depolarization and Glutamate 

      Kreitzer, Matthew A.; Collis, Leon P.; Molina, Anthony J.A.; Smith, Peter J. S; Malchow, Robert Paul (Rockefeller University Press, 2007-07-30)
      Self-referencing H+-selective microelectrodes were used to measure extracellular proton fluxes from cone-driven horizontal cells isolated from the retina of the catfish (Ictalurus punctatus). The neurotranmitter glutamate ...
    • Modulation of Neurotransmission by GPCRs Is Dependent upon the Microarchitecture of the Primed Vesicle Complex 

      Hamid, Edaeni; Church, Emily; Wells, Christopher A; Zurawski, Zack; Hamm, Heidi E; Alford, Simon (Society for Neuroscience, 2014-01-02)
      Gi/o-protein-coupled receptors (GPCRs) ubiquitously inhibit neurotransmission, principally via Gβγ, which acts via a number of possible effectors. GPCR effector specificity has traditionally been attributed to Gα, based ...
    • Molecular Microdomains in a Sensory Terminal, the Vestibular Calyx Ending 

      Lysakowski, Anna; Gaboyard-Niay, Sophie; Calin-Jageman, Irina; Chatlani, Shilpa; Price, Steven D.; Eatock, Ruth Anne (Society for Neuroscience, 2011-07-06)
      Many primary vestibular afferents form large cup-shaped postsynaptic terminals (calyces) that envelope the basolateral surfaces of type I hair cells. The calyceal terminals both respond to glutamate released from ribbon ...
    • Moving forward: fostering the next generation of Earth stewards in the STEM disciplines 

      Marshall, Kellen; Ortiz-Torres, Dorimar; Colón-Rivera, Ricardo J.; Soto-Santiago, Francisco J.; Flower, Charles E. (Ecological Society of America, 2013-09)
      Graduate students in the science, technology, engineering, and mathematics (STEM) disciplines struggle with developing research agendas that balance the overall goals of their work with questions of civic concern. The Earth ...
    • Neurexin in embryonic Drosophila neuromuscular junctions 

      Chen, Kaiyun; Gracheva, Elena O.; Yu, Szi-Chieh; Sheng, Qi; Richmond, Janet; Featherstone, David E. (Public Library of Science, 2010-06-14)
      Background: Neurexin is a synaptic cell adhesion protein critical for synapse formation and function. Mutations in neurexin and neurexin-interacting proteins have been implicated in several neurological diseases. Previous ...
    • Niche and host-associated functional signatures of the root surface microbiome. 

      Ofek-Lalzar, M.; Sela, N.; Goldman-Voronov, M.; Green, S.J.; Hadar, Y.; Minz, D. (Nature Publishing Group, 2015-09-18)
      Plant microbiomes are critical to host adaptation and impact plant productivity and health. Root-associated microbiomes vary by soil and host genotype, but the contribution of these factors to community structure and ...
    • Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity. 

      Ma, S; Lee, SG; Kim, EB; Park, TJ; Seluanov, A; Gorbunova, V; Buffenstein, R; Seravalli, J; Gladyshev, VN (Elsevier, 2015-11-17)
      Trace elements are essential to all mammals, but their distribution and utilization across species and organs remains unclear. Here, we examined 18 elements in the brain, heart, kidney, and liver of 26 mammalian species ...
    • Organization of the Mammalian Ionome According to Organ Origin, Lineage Specialization, and Longevity. 

      Ma, S; Lee, SG; Kim, EB; Park, TJ; Seluanov, A; Gorbunova, V; Buffenstein, R; Seravalli, J; Gladyshev, VN (Elsevier (Cell Press), 2015-11-17)
      Trace elements are essential to all mammals, but their distribution and utilization across species and organs remains unclear. Here, we examined 18 elements in the brain, heart, kidney, and liver of 26 mammalian species ...
    • Patterning the dorsal-ventral axis of the wasp Nasonia vitripennis 

      Buchta, Thomas; Özüak, Orhan; Stappert, Dominik; Roth, Siegfried; Lynch, Jeremy A. (Elsevier, 2013-09)
      Regulatory networks composed of interacting genes are responsible for pattern formation and cell type specification in a wide variety of developmental contexts. Evolution must act on these regulatory networks in order to ...
    • Phylogeny of a Genomically Diverse Group of Elymus (Poaceae) Allopolyploids Reveals Multiple Levels of Reticulation 

      Mason-Gamer, Roberta J. (Public Library of Science, 2013-11-01)
      The grass tribe Triticeae (=Hordeeae) comprises only about 300 species, but it is well known for the economically important crop plants wheat, barley, and rye. The group is also recognized as a fascinating example of ...
    • Physical Features of Intracellular Proteins that Moonlight on the Cell Surface 

      Amblee, V.; Jeffery, CJ (Public Library of Science, 2015)
      Moonlighting proteins comprise a subset of multifunctional proteins that perform two or more biochemical functions that are not due to gene fusions, multiple splice variants, proteolytic fragments, or promiscuous enzyme ...
    • Plant Parentage, Pollination, and Dispersal: How DNA microsatellites have altered the landscape 

      Ashley, Mary V. (Taylor & Francis, 2010-05)
      DNA microsatellites provide plant ecologists with molecular markers precise enough to assign parentage to seeds and seedlings. This allows the exact distance and trajectory of successful pollen to be traced to characterize ...
    • Plasticity in Bundle Sheath Extensions of Heterobaric Leaves 

      Lynch, Douglas J.; McInerney, Francesca A.; Kouwenberg, Lenny L.R.; Gonzalez-Meler, Miquel A. (Botanical Society of America, 2012-07)
      Premise of the study: Leaf venation is linked to physiological performance, playing a critical role in ecosystem function. Despite the importance of leaf venation, associated bundle sheath extensions (BSEs) remain largely ...
    • pMINERVA: A Donor-Acceptor System for the in vivo Recombineering of scFv into IgG Molecules. 

      Weiner, M.P.; Kay, B.K.; Wang, D.; Zhao, Q.; Holland, E.G.; Magadan, C.M.; Fuller, E.P.; Kiss, M.M.; Batonick, M. (Elsevier, 2016-04)
      Phage display is the most widely used method for selecting binding molecules from recombinant antibody libraries. However, validation of the phage antibodies often requires early production of the cognate full-length ...