Now showing items 1-6 of 6
Ameloblastin Modulates Osteoclastogenesis through the Integrin/ERK Pathway
Proteins of the extracellular matrix often have multiple functions to facilitate complex tasks ranging from signaling to structural support. Here we have focused on the function of one of the matrix proteins expressed in ...
Ameloblastin Inhibits Cranial Suture Closure by Modulating Msx2 Expression and Proliferation
(PLoS One, 2013-04)
Deformities of cranial sutures such as craniosynostosis and enlarged parietal foramina greatly impact human development and quality of life. Here we have examined the role of the extracellular matrix protein ameloblastin ...
Successful Periodontal Ligament Regeneration by Periodontal Progenitor Preseeding on Natural Tooth Root Surfaces
(Mary Ann Liebert, 2011-03-09)
The regeneration of lost periodontal ligament (PDL) and alveolar bone is the purpose of periodontal tissue engineering. The goal of the present study was to assess the suitability of 3 odontogenic progenitor populations ...
CP27: Expression, Regulation, and Function of a Chromatin Complex Member
CP27 is a novel gene involved in early vertebrate development that features a distinct expression pattern during development. The cp27 gene contains an open reading frame of 295 amino acids corresponding to a predicted ...
Apatite Microtopographies Instruct Signaling Tapestries for Progenitor-Driven New Attachment of Teeth
(Mary Ann Liebert, 2011-02)
Dimension and structure of extracellular matrix surfaces have powerful influences on cell shape, adhesion, and gene expression. Here we show that natural tooth root topographies induce integrin-mediated extracellular matrix ...
Enamel-Related Gene Products in Calvarial Development
(Sage Publications, 2013-07)
Enamel-related gene products (ERPs) are detected in non-enamel tissues such as bone. We hypothesized that if functional, ERP expression corresponds with distinct events during osteoblast differentiation and affects bone ...