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    • The structure of ribosome-lankacidin complex reveals ribosomal sites for synergistic antibiotics 

      Auerbach, Tamar; Mermershtain, Inbal; Davidovich, Chen; Bashan, Anat; Belousoff, Matthew; Wekselman, Itai; Zimmerman, Ella; Xiong, Liqun; Klepacki, Dorota; Mankin, Alexander; Yonath, Ada (National Academy of Sciences, 2010)
      Crystallographic analysis revealed that the 17-member polyketide antibiotic lankacidin produced by Streptomyces rochei, binds at the peptidyl transferase center of the ubacterial large ribosomal subunit. Biochemical and ...