Now showing items 1-3 of 3
Development of Co-solvent Freeze-Drying Method for the Encapsulation of Waterinsoluble Thiostrepton in Sterically Stabilized Micelles
The purpose of this work was to develop a practical and scalable method to encapsulate the hydrophobic antibiotic thiostrepton (TST) in sterically stabilized micelles (SSM). Using the conventional method of thin-film ...
Diazaquinomycin Biosynthetic Gene Clusters from Marine and Freshwater Actinomycetes
(American Chemical Society, 2019-03-21)
Tuberculosis is an infectious disease of global concern. Members of the diazaquinomycin (DAQ) class of natural products have shown potent and selective activity against drug-resistant Mycobacterium tuberculosis. However, ...
Frequency of “on-label” use of intravenous diltiazem for rate control in patients with acute-onset atrial fibrillation or atrial flutter
(Oxford University Press (OUP), 2019-02-01)
Background: Intravenous (IV) diltiazem is indicated for acute atrial fibrillation or flutter (AFF) but real-world dosing strategies often differ from labeling. Objective: To characterize “on-label” use of IV diltiazem in ...