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dc.contributor.advisorGrabiner, Mark D.en_US
dc.contributor.authorPater, Mackenzie L.en_US
dc.date.accessioned2015-07-21T18:04:38Z
dc.date.available2017-07-22T09:30:21Z
dc.date.created2015-05en_US
dc.date.issued2015-07-21
dc.date.submitted2015-05en_US
dc.identifier.urihttp://hdl.handle.net/10027/19591
dc.description.abstractFall risk is nearly 2.5 times greater in people with osteoarthritis (OA) compared to those without OA. However, the underlying mechanisms explaining this increased risk are unknown. This dissertation, which focused on trip-related falls, identified biomechanical risk factors that contribute to the increased fall risk of people with OA. The focus of the first experiment was to explain this increased fall risk by relating gait biomechanics to fall history in women with and without knee OA. Twice the number of women with knee OA reported having at least one trip-related fall in the previous year. This clinically meaningful difference was not related to between-group differences in minimum toe clearance, suggesting that the higher incidence of falls may not reflect an increased likelihood of unexpectedly contacting an obstacle during gait. The focus of the second experiment was to determine if the increase in trip-related fall risk of the OA group following large disturbances to dynamic stability was due to impaired recovery stepping responses. Women with and without knee OA were subjected to two types of large perturbations mimicking trips. Following both perturbations, women with knee OA displayed impaired control of the trunk evidenced by trunk kinematics previously shown to statistically discriminate fallers from non-fallers for healthy older adults. Furthermore, these kinematics have been shown to be modifiable using task-specific perturbation training. The third study evaluated if task-specific perturbation training could improve kinematics related to the recovery stepping response following large, treadmill-delivered postural perturbations requiring a step(s) to avoid falling. Recovery step kinematics of women with OA improved to the same extent as women in the control group. Collectively, the results of these experiments indicate that, in part, the increased risk of falls associated with OA is attributable to the same biomechanical variables that have been previously shown to explain falls by middle aged and older community-dwelling women without knee OA. Furthermore, the results strongly suggest that task-specific perturbation training has the potential to be an effective and efficient fall-prevention intervention for many people with knee OA.en_US
dc.language.isoenen_US
dc.rightsen_US
dc.rightsCopyright 2015 Mackenzie L. Pateren_US
dc.subjectfallsen_US
dc.subjectknee osteoarthritisen_US
dc.subjectrecovery responseen_US
dc.subjectagingen_US
dc.subjectfall preventionen_US
dc.subjecttask-specificityen_US
dc.titleAssociating Knee Osteoarthritis with Fall Risk: Implications for Interventionsen_US
thesis.degree.departmentKinesiology and Nutritionen_US
thesis.degree.disciplineKinesiology, Nutrition, and Rehabilitation Sciencesen_US
thesis.degree.grantorUniversity of Illinois at Chicagoen_US
thesis.degree.levelDoctoralen_US
thesis.degree.namePhD, Doctor of Philosophyen_US
dc.type.genrethesisen_US
dc.contributor.committeeMemberWalter, Charlesen_US
dc.contributor.committeeMemberFoucher, Kharmaen_US
dc.contributor.committeeMemberMessier, Stephen P.en_US
dc.contributor.committeeMemberShakoor, Najiaen_US
dc.type.materialtexten_US


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