Logo for the University of Illinois at Chicago
    • Login
    View Item 
    •   INDIGO Home
    • Dissertations and Theses at UIC
    • UIC Dissertations and Theses
    • View Item
    •   INDIGO Home
    • Dissertations and Theses at UIC
    • UIC Dissertations and Theses
    • View Item
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Examining Sources Of Variation In Developing A Societal Health State Value Set

    Thumbnail
    View/Open
    LAW-DISSERTATION-2018.pdf (2.108Mb)
    Date
    2018-08-10
    Author
    Law, Ernest H
    Metadata
    Show full item record
    Abstract
    This dissertation aimed to examine sources of variation in developing a societal value set for health preferences using a generic preference-based measure. Three separate studies were conducted to assess the differences due to differences in the descriptive system, time, and advance directives status. The first study sought to compare and contrast EQ-5D-5L (‘5L’) and EQ-5D-3L (‘3L’) societal value sets derived from a common sample. Compared to the 3L, value sets developed using the 5L exhibit a lower ceiling effect and improved measurement properties. There was a larger range of scale for the 3L compared to 5L; however, this difference was driven by differences in preference for the most severe level of problems in Mobility for the 3L (“confined to bed”) and 5L (“unable to walk about”). The second study aimed to better understand the implications of informed preferences and examined the association between advance directives for health care and health preferences. Advance directive completion was associated with lower values, implying greater willingness to trade years of life for better health, but not an increased likelihood of valuing health states as WTD. If advance directives are an indicator of a substantial proportion of the population with “informed” preferences, it has implications not only for intensive care decision making at the individual level, but also resource allocation based on cost-utility analysis at the group level. The final study assessed whether there were time-specific differences in health preferences between 2002 and 2017, accounting for demographic changes in the society as well as study designs. Health values in 2017 were modestly higher, implying individuals in 2017 were generally less willing to trade quantity for quality of life compared to 2002. The findings suggest that the era in which values were elicited may be an important reason to consider updating societal value sets. Overall, the work reported in this dissertation advances our understanding of how societal preferences can vary and will be important for informing health technology assessment, health care resource allocation decisions, and understanding how specific groups in society value health.
    Subject
    health preferences
    societal values
    health-related quality of life
    EQ-5D
    advance directives
    Type
    Thesis
    text
    Date available in INDIGO
    2018-11-27T16:29:23Z
    URI
    http://hdl.handle.net/10027/23037
    Collections
    • UIC Dissertations and Theses
    • Dissertations and Theses - Pharmacy

    DSpace software copyright © 2002-2015  DuraSpace
    Contact Us | Send Feedback | Privacy Statement
    Theme by 
    Atmire NV

    Browse

    All of INDIGOCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

    My Account

    LoginRegister

    Statistics

    View Usage Statistics

    DSpace software copyright © 2002-2015  DuraSpace
    Contact Us | Send Feedback | Privacy Statement
    Theme by 
    Atmire NV