Now showing items 1-2 of 2

    • Inhibition of Fast Axonal Transport by Pathogenic SOD1 Involves Activation of p38 MAP Kinase 

      Morfini, Gerardo A.; Bosco, Daryl A.; Brown, Hannah; Gatto, Rodolfo; Kaminska, Agnieszka; Song, Yuyu; Molla, Linda; Baker, Lisa; Marangoni, M. Natalia; Berth, Sarah; Tavassoli, Ehsan; Bagnato, Carolina; Tiwari, Ashutosh; Hayward, Lawrence J.; Pigino, Gustavo F.; Watterson, D. Martin; Huang, Chun-Fang; Banker, Gary; Brown Jr, Robert H.; Brady, Scott T. (PLoS One, 2013-06)
      Dying-back degeneration of motor neuron axons represents an established feature of familial amyotrophic lateral sclerosis (FALS) associated with superoxide dismutase 1 (SOD1) mutations, but axon-autonomous effects of ...
    • The Sphingolipid Psychosine Inhibits Fast Axonal Transport in Krabbe Disease by Activation of GSK3 and Deregulation of Molecular Motors 

      Castelvetri, Ludovico Cantuti; Givogri, Maria I.; Hebert, Amy; Smith, Benjamin; Song, Yuyu; Kaminska, Agnieszka; Lopez-Rosas, Aurora; Morfini, Gerardo; Pigino, Gustavo; Sands, Mark; Brady, Scott T.; Bongarzone, Ernesto R. (Society for Neuroscience, 2013-06)
      Loss of function of galactosylceramidase lysosomal activity causes demyelination and vulnerability of various neuronal populations in Krabbe disease. Psychosine, a lipid-raft-associated sphingolipid that accumulates in ...