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Nitric oxide donor [Ru(terpy)(bdq)NO]3+ induces uncoupling and phosphorylation of endothelial nitric oxide synthase promoting ROS and peroxynitrite production

Potje, Simone, R.; Chen, Zhenlong; Oliveira, Suellen D'Arc; Dull, Randal, O.; Bendhack, Lusiane, M.; Da Silva, Roberto, S.; Bonini, Marcelo, G.; Antoniali, Cristina; Minshall, Richard, D. (Elsevier, 2017-11-01)

TERPY is a nitric oxide (NO) donor that promotes relaxation of the mesenteric artery and aorta in rats. We sought to investigate whether it acts as both an NO donor and endothelial NO synthase (eNOS) activator, as shown ...