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    • Minimizing Cytosol Dilution in Whole-Cell Patch-Clamp Experiments 

      Inayat, Samsoon; Pinto, Lawrence H.; Troy, John B. (Institute of Electrical and Electronics Engineers, 2013-07)
      During a conventional whole-cell patch clamp experiment, diffusible cytosolic ions or molecules absent in the pipette solution can become diluted by a factor of one million or more, leading to diminished current or fluorescent ...