Browsing Publications - Anesthesiology by Author "Petukhov, Pavel A."

Now showing items 1-1 of 1

    • An Angiotensin I-Converting Enzyme Mutation (Y465D) Causes a Dramatic Increase in Blood ACE via Accelerated ACE Shedding 

      Danilov, Sergei M.; Gordon, Kerry; Nesterovitch, Andrew B.; Lu¨ nsdorf, Heinrich; Chen, Zhenlong; Castellon, Maricela; Popova, Isolda A.; Kalinin, Sergey; Mendonca, Emma; Petukhov, Pavel A.; Schwartz, David E.; Minshall, Richard D.; Sturrock, Edward D. (Public Library of Science, 2011-10)
      Background: Angiotensin I-converting enzyme (ACE) metabolizes a range of peptidic substrates and plays a key role in blood pressure regulation and vascular remodeling. Thus, elevated ACE levels may be associated with an ...