Now showing items 1-5 of 5
The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with increased body mass index and insulin resistance measures in bipolar disorder and schizophrenia
(Wiley Periodicals Inc., 2015)
Objectives: We tested the hypothesis that a common functional variant in brain-derived neurotrophic factor (BDNF), Val66Met, which has been shown to be associated with increased body mass index (BMI) in schizophrenia ...
Posaconazole: Use in the Prophylaxis and Treatment of Fungal Infections.
(Georg Thieme Verlag KG Stuttgart · New York, 2015-10)
Posaconazole, a fluorinated triazole antifungal drug, is approved by the U.S. Food and Drug Administration (FDA) for (1) prophylaxis against Aspergillus and Candida infections in immunocompromised patients at high risk for ...
Genetic Predictor of Working Memory and Prefrontal Function in Women with HIV
(Springer Verlag, 2015-02)
The Val158Met (rs4680) single nucleotide polymorphism (SNP) of the catechol-O-methyltransferase gene (COMT) influences executive function and prefrontal function through its effect on dopamine (DA) metabolism. Both HIV and ...
Sex differences in GABAergic gene expressions occur in the anterior cingulate cortex in schizophrenia.
(Elsevier Inc., 2015)
GABAergic dysfunction has been strongly implicated in the pathophysiology of schizophrenia. In this study, we analyzed the expression levels of several GABAergic genes in the anterior cingulate cortex (ACC) of ...
Sex differences in glutamate receptor gene expression in major depression and suicide
(Nature Publishing Group, 2015)
Accumulating data indicate that the glutamate system is disrupted in major depressive disorder (MDD), and recent clinical research suggests that ketamine, an antagonist of the N-methyl-D-aspartate (NMDA) glutamate receptor ...