Now showing items 1-1 of 1

    • Insulin and IGF-I Inhibit GH Synthesis and Release in Vitro and in Vivo by Separate Mechanisms 

      Gahete, Manuel D.; Córdoba-Chacón, José; Lin, Qing; Brüning, Jens C.; Kahn, C. Ronald; Castaño, Justo P.; Christian, Helen; Luque, Raúl M.; Kineman, Rhonda D. (Endocrine Society, 2013-07)
      IGF-I is considered a primary inhibitor of GH secretion. Insulin may also play an important role in regulating GH levels because insulin, like IGF-I, can suppress GH synthesis and release in primary pituitary cell cultures ...